DISEASES

Disease-gene associations mined from literature

Literature associating TRIP6 and lipoma

TRIP6 [ENSP00000200457]

Thyroid receptor-interacting protein 6; Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF- kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. ; Belongs to the zyxin/ajuba family.

Synonyms:  TRIP6,  TRIP6p,  hTRIP6,  H7BZE2,  Q15654 ...

Linkouts:  STRING  Pharos  UniProt  OMIM