DISEASES

Disease-gene associations mined from literature

Literature associating GUCA1A and cone-rod dystrophy

GUCA1A [ENSP00000053469]

Guanylyl cyclase-activating protein 1; Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated . This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure (By similarity). May be involved in cone photoreceptor light response and recovery of response in bright light (By similarity).

Synonyms:  GUCA1A,  GUCA1Ap,  hGUCA1A,  A6PVH5,  A6PVH5p ...

Linkouts:  STRING  Pharos  UniProt  OMIM