DISEASES

Disease-gene associations mined from literature

Literature associating MRI1 and discitis

MRI1 [ENSP00000040663]

Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Synonyms:  MRI1,  MRI1p,  hMRI1,  Q9BV20,  Q9BV20p ...

Linkouts:  STRING  Pharos  UniProt  OMIM