Literature associating DVL2 and exudative vitreoretinopathy
DVL2 [ENSP00000005340]
Segment polarity protein dishevelled homolog DVL-2; Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling; Belongs to the DSH family.
Synonyms: DVL2, DVL2p, hDVL2, I3L0M7, I3L0Z8 ...